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Hello. I'm reading Luescher's, "Manual of Parrot Behavior," and I have a question. On page 204 of chapter 17 you find this statement in reference toPBFD:

"Diagnosis is made through histopathology of an affected feather in combination with a PCR probe to help confirm the disease."

Can you tell me what a PCR probe is? Thank you.

Cindi Eppers

Answered by Ellen K. Cook, D.V.M.:

Hi Cindi, A PCR (Polymerase Chain Reaction) probe is a DNA test done on a blood sample to determine the presence of DNA segments of specific viruses or other organisms (Chlamydia, Mycoplasma) in the bird's blood. This does not always mean the presence of disease. Laboratory tests must be interpreted in the light of a complete history and physical examination by a qualified avian veterinarian.

Thanks for the great question!

Dr. Cook

filed under: Health and Nutrition

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